Hypersensitivity to penicillins. History of allergy eg, bronchial asthma, rash, urticarial. Serious renal function disorder. Vit K deficiency may develop in patients w/ poor oral nutrition, receiving parenteral nutrition, elderly or in a debilitated state. False +ve results may occur in Benedict's & Fehling's soln, & clinitest. +ve direct Coomb's test may occur. Pregnancy & lactation. Premature & newborn infants.
Shock, hypersensitivity, granulocytopenia or eosinophila, increase in GOT & GPT or alkaline phosphatase; abdominal pain or frequent diarrhea, vomiting, stomach discomfort, heartburn or anorexia, nausea.
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