Patients w/ asthma, increased IOP, narrow angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction & bladder-neck obstruction. May cause somnolence. Hyperemesis gravidarum. Gradually taper dose at discontinuation. Assess additional levels of vit B
6 from diet & supplements. False +ve urine screening tests for methadone, opiates, & phencyclidine phosphate (PCP). Contains allura red AC Al lake (E129) which may cause allergic reactions. Not recommended to use concomitantly w/ CNS depressants including alcohol. May affect ability to drive & use machines. Lactation. Childn <18 yr.