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IV Drip Infusion: Usual daily dosage of Fosmicin for IV use: Adults: 4 g/day (potency). Children: 100-200 mg/day (potency)/kg; both of these are given by IV drip infusion in 2 divided doses. Each dose is dissolved in 100-500 mL of IV fluid and infused over a period of 1-2 hrs.
IV Injection: Adults and children: The usual daily dosages are the same as for IV drip infusion, but given in 2 divided doses. As a solvent, 20 mL of water for injection or 5% glucose solution for injection is used to dissolve 1-2 g of Fosmicin for IV use. The IV injection must be performed over a period of >5 min.
The previously mentioned daily dosages may be adjusted according to the age of the patient and the severity of the infection.
Meningitis: 6-12 g/day divided 8 hrly.
Osteomyelitis or Bone and Joint Infections: 4 g every 12 hr.
