Reduced effect of formoterol with β-blockers. Additive effects of formoterol with theophylline or other β-adrenergic drugs. Prolonged QTc-interval & increased risk of ventricular arrhythmias with quinidine, disopyramide, procainamide, phenothiazines, antihistamines, MAOIs, TCAs. Impaired cardiac tolerance with L-dopa, L-thyroxine, oxytocin, alcohol. May precipitate hypertensive reactions with furazolidone, procarbazine. Hypokalaemic effect with xanthine derivatives, steroids, diuretics. Disulfiram, metronidazole.