General: Itopride hydrochloride enhances the action of acetylcholine and may produce cholinergic side effects.
Data on long-term use are not available.
Effects on ability to drive and use machine: No studies on the effects on the ability to drive and use machines have been performed.
Fertility: No human data on the effect of itopride on fertility are available; however, animal studies do not indicate harmful effects of itopride (see Pharmacology: Toxicology: Preclinical Safety Data under Actions).
Use in Children: Safety of this product in children under the age of 16 has not been established.
Use in the Elderly: In general, appropriate caution should be exercised in the administration and monitoring of itopride hydrochloride in elderly patients reflecting the greater frequency of decreased hepatic, renal function, and of concomitant disease or other drug therapy.