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Pregnancy: Safe use of spironolactone during pregnancy has not been established. The drug should be used during pregnancy only when the potential benefits outweigh the possible risks to the fetus.
Lactation: Since canrenone, a metabolite of spironolactone, is distributed into milk, spironolactone should not be used in nursing woman. If use of spironolactone is deemed essential, nursing should be discontinued and an alternative method of infant feeding should be instituted.
