Hyrimoz Caution For Usage

Incompatibilities: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.
Instructions for use, Special precautions for disposal and other handling: To help avoid possible infections and to ensure that the patient uses the medicine correctly, it is important that the patient follow these instructions.
Be sure to read, understand, and follow these Instructions for Use before injecting Hyrimoz.
The healthcare provider should show how to prepare and inject Hyrimoz properly using the pre-filled syringe before using it for the first time. Talk to the healthcare provider if there are any questions.
It is important that the patient: Does not open the outer box until they are ready to use the syringe.
Does not use the syringe if the seals of the blister are broken, as it may not be safe for use.
Never leave the syringe unattended where others might tamper with it.
Does not shake the syringe.
If the patient drops the syringe, do not use it if it looks damaged, or if they dropped it with the needle cap removed.
Does not remove the needle cap until just before they give the injection.
Be careful not to touch the needle guard wings before use. Touching them may cause the needle guard to be activated too early. Do not remove the finger flange before the injection.
Inject Hyrimoz 15-30 minutes after taking it out of the refrigerator for a more comfortable injection.
Throw away the used syringe right away after use. Do not re-use a syringe. See Disposing of used syringes as follows.
How to store Hyrimoz: Store outer carton of syringes in a refrigerator, between 2°C to 8°C.
When needed (for example when the patient is travelling), Hyrimoz may be stored at room temperature (up to 25°C) for a maximum period of 21 days - be sure to protect it from light. Once removed from the refrigerator for room temperature storage, the pre-filled syringe must be used within 21 days or discarded, even if it is later returned to the refrigerator. The patient should record the date when the pre-filled syringe is first removed from the refrigerator, and the date after which it should be discarded.
Keep the syringes in the original carton until ready to use to protect from light.
Do not store the syringes in extreme heat or cold.
Do not freeze the syringes.
What does the patient need for the injection: Place the following items on a clean, flat surface. Included in the carton is: Hyrimoz pre-filled syringe/s. Each syringe contains 40 mg/0.8 ml of Hyrimoz.
Not included in the carton are: Alcohol wipe, Cotton ball or gauze, Sharps disposal container.
See Disposing of used syringes at the end of these Instructions for Use.
Preparing the syringe: For a more comfortable injection, take the blister containing the syringe out of the refrigerator and leave it unopened on the work surface for about 15 to 30 minutes so that it reaches room temperature.
Take the syringe out of the blister.
Look through the viewing window. The solution should be colourless to slightly yellowish as well as clear to slightly opalescent. Do not use if any particulates and / or discolorations are observed. If the patient is concerned with the appearance of the solution, then contact the pharmacist for assistance.
Do not use the syringe if it is broken or the needle guard is activated. Return the syringe and the package it came in to the pharmacy.
Look at the expiration date (EXP) on the syringe. Do not use the syringe if the expiration date has passed.
Contact the pharmacist if the syringe fails any of the previously mentioned checks.
Choosing the injection site: The recommended injection site is the front of the thighs. The patient may also use the lower abdomen, but not the area 5 cm around the navel (belly button).
Choose a different site each time the patient give themselves an injection.
Do not inject into areas where the skin is tender, bruised, red, scaly, or hard. Avoid areas with scars or stretch marks. If the patient has psoriasis, they should NOT inject directly into areas with psoriasis plaques.
Cleaning the injection site: Wash hands well with soap and water.
Using a circular motion, clean the injection site with an alcohol wipe. Leave it to dry before injecting.
Do not touch the cleaned area before injecting.
Giving the injection: Carefully pull the needle cap straight off to remove it from the syringe.
Discard the needle cap.
The patient may see a drop of liquid at the end of the needle. This is normal.
Gently pinch the skin at the injection site.
Insert the needle into the skin.
Push the needle all the way in to ensure that the medication can be fully administered.
Hold the syringe.
Slowly press down on the plunger as far as it will go, so that the plunger head is completely between the needle guard wings.
Keep the plunger pressed fully down while the patient holds the syringe in place for 5 seconds.
Keep the plunger fully pressed down while carefully lifting the needle straight out from the injection site and let go of the skin.
Slowly release the plunger and allow the needle safety guard to automatically cover the exposed needle.
There may be a small amount of blood at the injection site. The patient can press a cotton ball or gauze onto the injection site and hold it for 10 seconds. Do not rub the injection site. The patient may cover the injection site with a small adhesive bandage, if needed.
Disposing of used syringes: Dispose of the used syringe in a sharps container (closable, puncture-resistant container).
For the safety and health of the patient and others, needles and used syringes must never be re-used.
Do not throw away any medicines via wastewater or household waste. Ask the doctor or pharmacist how to throw away medicines the patient no longer uses.
These measures will help protect the environment.
Any unused product or waste material should be disposed of in accordance with local requirements.
If the patient has any questions, please talk to a doctor, pharmacist or nurse who is familiar with Hyrimoz.