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Adults (including the elderly): One eye drop in the affected eye(s) once daily.
Pediatric population: Safety and effectiveness in children and adolescents has not been established.
Dosage adjustment in hepatic/renal impairment: Latanoprost has not been studied in patients with hepatic impairment and should therefore be used with caution in such patients.
Method of administration: 1. Contact lenses should be removed before instillation of the eye drops and may be reinserted after 15 minutes.
2. If more than one topical ophthalmic drug is being used, the drugs should be administered at least five minutes apart.
3. When using nasolacrimal occlusion or closing the eyelids for 2 minutes, the systemic absorption is reduced. This may result in a decrease in systemic side effects and an increase in local activity.
