No formal interaction studies have been performed.
In clinical trials for treatment of visual impairment due to DME, the outcome with regards to visual acuity or central retinal thickness in patients treated with Lucentis was not affected by concomitant treatment with thiazolidinediones (see Pharmacology: Pharmacodynamics: CLINICAL STUDIES under Actions).
For the adjunctive use of laser photocoagulation and Lucentis in DME and BRVO, see Pharmacology: Pharmacodynamics: CLINICAL STUDIES under Actions and DOSAGE & ADMINISTRATION.