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Pregnancy: There are no adequate data from the use of Neupro in pregnant women. Animal studies do not indicate any teratogenic effects in rats and rabbits but embryo-toxicity was observed in rats and mice at materno-toxic doses (see Pharmacology: Toxicology: Preclinical safety data under Actions). The potential risk for humans is unknown. Rotigotine should not be used during pregnancy.
Breastfeeding: Because rotigotine decreases prolactin secretion in humans, inhibition of lactation is expected. Studies in rats have shown that rotigotine and/or its metabolite(s) is excreted in breast milk. In the absence of human data, breastfeeding should be discontinued.
