Nexium Caution For Usage

Incompatibilities: Tablet: Not applicable.
Injection: This medicinal product should not be used with other medicinal products except those mentioned in Instructions for use and handling as follows.
Instructions for use and handling: Tablet: Administration through gastric tube: 1. Put the tablet into an appropriate syringe and fill the syringe with approximately 25 mL water and approximately 5 mL air. For some tubes, dispersion in 50 mL water is needed to prevent the pellets from clogging the tube.
2. Immediately shake the syringe for approximately 2 minutes to disperse the tablet.
3. Hold the syringe with the tip up and check that the tip has not clogged.
4. Attach the syringe to the tube whilst maintaining the previously mentioned position.
5. Shake the syringe and position it with the tip pointing down. Immediately inject 5-10 mL into the tube. Invert the syringe after injection and shake (the syringe must be held with the tip pointing up to avoid clogging of the tip).
6. Turn the syringe with the tip down and immediately inject another 5-10 mL into the tube. Repeat this procedure until the syringe is empty.
7. Fill the syringe with 25 mL of water and 5 mL of air and repeat step 5 if necessary to wash down any sediment left in the syringe. For some tubes, 50 mL water is needed.
Injection: The reconstituted solution should be inspected visually for particulate matter and discoloration prior to administration. Only clear solution should be used. For single use only. When administering a 20 mg dose only half of the reconstituted solution should be used. Any unused solution should be discarded.
Injection: A solution for injection is prepared by adding 5 mL of 0.9% sodium chloride for intravenous use to the vial with esomeprazole. The reconstituted solution for injection is clear and colorless to very slightly yellow.
The degradation of reconstituted solution is highly pH dependent and the product must therefore only be reconstituted in the specified volume of 0.9% sodium chloride for intravenous use. The reconstituted solution should not be mixed or co-administered in the same infusion set with any other drug.
Infusion: A solution for infusion is prepared by dissolving the content of one vial with esomeprazole in up to 100 mL 0.9% sodium chloride for intravenous use.
The reconstituted solution for infusion is clear and colorless to very slightly yellow.
Infusion 80 mg: A solution for infusion is prepared by dissolving the content of two vials of esomeprazole 40 mg in up to 100 ml of 0.9% sodium chloride for intravenous use.
The degradation of reconstituted solution is highly pH dependent and the product must therefore only be reconstituted in the specified volume of 0.9% sodium chloride for intravenous use.
The reconstituted solution should not be mixed or co-administered in the same infusion set with any other drug.
The reconstituted solution should be administered separately from other drugs.