Adult Duodenal ulcer 20 mg daily for 4 wk. Severe case: 40 mg once daily for 4 wk.
Duodenal ulcer associated w/ H. pylori infection 20-40 mg + clarithromycin 500 mg & amoxicillin 1 g bid for 10-14 days.
Gastric ulcer 40 mg once daily for 8 wk.
Dyspepsia 10-20 mg once daily for 2-4 wk.
Erosive oesophagitis Initial dose: 20 mg once daily for 4-8 wk. Maintenance dose: 20 mg once daily for max of 12 mth.
GERD 20 mg once daily for 4-8 wk.
Hypersecretory conditions eg, Zollinger-Ellison syndrome 60 mg once daily. Max: 120 mg daily in divided doses. Duration: Up to 5 yr in some patients.
Aspiration prophylaxis 40 mg in evening before surgery, thereafter, 40 mg 2-6 hr prior to operation.
Childn Duodenal ulcer associated w/ H. pylori infection 1-2 mg/kg once daily. Max: 40 mg daily or 1-2 mg/kg daily.
Erosive oesophagitis & GERD in ≥1 yr weighing ≥ 20 kg 20 mg once daily. Max: 20 mg daily or 3 mg/kg daily.
Hepatic impairment 10-20 mg once daily.
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