Orgalutran

Orgalutran

ganirelix

Manufacturer:

Organon

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Ganirelix
Indications/Uses
Prevention of premature LH surges in women undergoing controlled ovarian hyperstimulation (COH) for assisted reproduction techniques (ART).
Dosage/Direction for Use
SC 0.25 mg once daily, starting on day 6 of FSH administration. COH w/ FSH May start at day 2 or 3 of menses. High responders Starting treatment on day 5 may prevent early LH rise.
Contraindications
Hypersensitivity to ganirelix, dry natural rubber/latex & gonadotrophin-releasing hormone (GnRH) or any other GnRH analogue. Moderate or severe renal or hepatic impairment. Pregnancy & lactation.
Special Precautions
Discontinue if hypersensitivity reaction is suspected. Ovarian hyperstimulation syndrome (OHSS). Increased incidence of ectopic pregnancies in infertile women w/ tubal abnormalities undergoing assisted reproduction particularly IVF; congenital malformations after ART. Women w/ signs & symptoms of severe allergic conditions; weighing <50 kg or >90 kg.
Adverse Reactions
Local inj site skin reactions (predominantly redness w/ or w/o swelling), malaise; headache; nausea. Pelvic pain, abdominal distension, OHSS, ectopic pregnancy & spontaneous abortion.
MIMS Class
Trophic Hormones & Related Synthetic Drugs
ATC Classification
H01CC01 - ganirelix ; Belongs to the class of anti-gonadotropin-releasing hormones. Used in hypothalamic hormone preparations.
Presentation/Packing
Form
Orgalutran soln for inj 0.25 mg/0.5 mL
Packing/Price
1's;5 × 1's
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