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Concurrent administration of Phenobarbital, phenytoin may increase cholecalciferol metabolism.
Concurrent administration of thiazides may risk of hypercalcemia.
Concurrent administration of cholestyramine or colestipol hydrochloride may result in decreased intestinal absorption of vitamin D analogs.
Concurrent administration of orlistat may result in decreased GI absorption of fat-soluble vitamins such as vitamin D analogs. At least 2 hours should elapse between (before or after) any orlistat dose and vit D analog administration.
Concurrent use of vitamin D analogs and cardiac glycosides may result in cardiac arrhythmias.
