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Contraindications for use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia: Hypersensitivity to the active substance or to any of the excipients or to murine proteins.
Active, severe infections (see Precautions).
Patients in a severely immunocompromised state.
Contraindications for use in rheumatoid arthritis: Hypersensitivity to the active substance or to any of the excipients or to murine proteins.
Active, severe infections (see Precautions).
Patients in a severely immunocompromised state.
Severe heart failure (New York Heart Association Class IV) or severe, uncontrolled cardiac disease.
