Discontinue treatment if Ab-mediated pure red cell aplasia develops & test for erythropoietin Abs; anaphylactoid reactions occurs. Determine hematocrit in HIV-infected patients w/ zidovudine-induced anemia or cancer patients w/ chemotherapy-induced anemia at least once a wk, & at least once or twice wkly in patients w/ chronic renal failure anemia. Monitor BP in patients w/ underlying history of HTN or CV disease. Preexisting seizure order. Monitor serum & tissue iron stores during therapy.
Acute or chronic inflammation, infection, neoplastic disease or malignancy, underlying myelodysplastic disorders, marrow suppression from uremia, Al overload, hyperparathyroidism/osteitis fibrosa cystica, hypersplenism, hyacute or chronic blood loss, erythrocyte enzyme abnormalities, folic acid or vit B
12 deficiency. Pregnancy & lactation. Childn. Elderly.
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