Caution should be used in administering the drug in patients with hyperuricemia or with a history of gout and/or under treatment with drugs that might be able to interfere with the metabolism and excretion of uric acid.
Nicergoline may potentiate the hypotensive effect of antihypertensive agents. Use with caution when taking this drug with antihypertensive agents especially beta blockers.
Avoid concomitant use in patient with porphyria.