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Overdosage with omeprazole has been reported rarely. Doses ranged from 2,400 mg (120 times the usual recommended dose). Symptom were transient and included confusion, drowsiness, blurred vision, tachycardia, nausea, diaphoresis, flushing, headache and dry mouth. No serious clinical outcome has been reported.
No specific antidote for omeprazole overdosage is known.
Treatment: Omeprazole are extensively protein bound and are not readily dialyzable. Treatment should be symptomatic and supportive.
