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Central nervous system (CNS) side effects including somnolence, fatigue, and asthenia have been reported in patients receiving levocetirizine. Patients taking levocetirizine should be advised to avoid activities requiring complete mental alertness or physical coordination. Concomitant use of levocetirizine with alcohol or other CNS depressants should be avoided.
Effects on Ability to Drive and Use Machines: Patients intending to drive, engaging in potentially hazardous activities or operating machinery should not exceed the recommended dose and should take their response to the medicinal product into account. In these sensitive patients, concurrent use with alcohol or other CNS depressants may cause additional reductions in alertness and impairment of performance.
