Avodart Dosage/Direction for Use

Avodart can be administered alone or in combination with the α-blocker tamsulosin 0.4 mg (see Pharmacology under Actions and Adverse Reactions).  
Avodart may be taken with or without food. The capsules should be swallowed whole and not chewed or opened, as contact with the capsule contents may result in irritation of the oropharyngeal mucosa.
Adult Males (Including Elderly): Recommended Dose: 1 capsule (0.5 mg) taken orally once daily.
Although an improvement may be observed at an early stage, it can take up to 6 months before a response to the treatment can be achieved.
Renal Impairment: The effect of renal impairment on dutasteride pharmacokinetics has not been studied. No adjustment in dosage is anticipated for patients with renal impairment (see Pharmacology: Pharmacokinetics under Actions).
Hepatic Impairment: The effect of hepatic impairment on dutasteride pharmacokinetics has not been studied so caution should be used in patients with mild o moderate hepatic impairment (see Pharmacology: Pharmacokinetics under Actions and Precautions). In patient with severe hepatic impairment, the use of dutasteride is contraindicated.
Administration: Avodart should be swallowed whole and may be taken with or without food.