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Brumed should not be given to patients with a history of, or active, peptic ulceration. It is contra-indicated in patients who have previously shown hypersensitivity reactions (e.g. asthma, rhinitis or urticaria) in response to Ibuprofen, aspirin or other non-steroidal anti-inflammatory drugs. Bronchospasm may be precipitated in patients suffering from, or with a previous history of, bronchial asthma.
Brumed is contraindicated: i) In patient with severe heart failure.
ii) For the treatment of peri-operative pain in the setting of coronary artery bypass graft surgery.
History of gastrointestinal bleeding or perforation related to previous NSAIDs therapy; active, or history of recurrent peptic ulcer/haemorrhage.
