Vial: Store as directed on outer package.
Do not freeze.
Keep the vial in the outer carton in order to protect from light.
Shelf life: After reconstitution: Chemical and physical stability of the reconstituted medicinal product have been demonstrated for 8 hours when stored below 30°C.
From a microbiological point of view, unless the method of reconstitution precludes the risk of microbial contamination, the product should be used immediately. If not used immediately, in-use storage times and conditions are the responsibility of user.
Pre-filled pen: The storage conditions are detailed on the packaging.
If necessary, the Nucala pre-filled pen can be removed from the refrigerator and kept in the unopened pack for up to 7 days at room temperature (up to 30°C), when protected from light. The pack should be discarded if left out of the refrigerator for more than 7 days.
The pre-filled pen must be administered within 8 hours once the pack is opened. The pack should be discarded if not administered within 8 hours.