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pms-IRBESARTAN (irbesartan) is contraindicated in: Patients who are hypersensitive to this drug or to any ingredient in the formulation, including any non-medicinal ingredient, or component of the container. For a complete listing, see Description.
Combination with aliskiren-containing drugs in patients with diabetes mellitus (type 1 or type 2) or moderate to severe renal impairment (GFR < 60 mL/min/1.73 m2) (see Cardiovascular and Renal under Precautions; and Interactions).
Combination with Angiotensin-Converting Enzyme Inhibitors (ACEIs) in patients with diabetic nephropathy (see Cardiovascular and Renal under Precautions; and Interactions).
Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption (due to the lactose component of pms-IRBESARTAN tablets).
Pregnant women (see Precautions and Use in Pregnancy & Lactation).
Nursing women (see Precautions and Use in Pregnancy & Lactation).
