Priorix Caution For Usage

Instructions for Use/Handling: Due to minor variation of its pH, the reconstituted vaccine may vary in colour from clear peach to fuchsia pink without deterioration of the vaccine potency.
The solvent and the reconstituted vaccine should be inspected visually for any foreign particulate matter and/or variation of physical aspects prior to reconstitution or administration. In the event of either being observed, do not use the solvent or the reconstituted vaccine.
Monodose presentation: Inject the entire contents of the syringe, using a new needle for administration.
Multidose (2 doses) presentation: When using a multidose vial, each dose of 0.5 ml should be withdrawn using a sterile needle and syringe; precautions should be taken to avoid contamination of the contents. A new needle should be used to administer each individual dose of the vaccine.
Instructions for reconstitution of the vaccine with the solvent presented in pre-filled syringe: Priorix must be reconstituted by adding the entire contents of the pre-filled syringe of solvent to the vial containing the powder.
To attach the needle to the syringe, refer to the instructions as follows.
Always hold the syringe by the barrel, not by the syringe plunger or the Luer Lock Adaptor (LLA), and maintain the needle in the axis of the syringe. Failure to do this may cause the LLA to become distorted and leak.
During assembly of the syringe, if the LLA comes off, a new vaccine dose (new syringe and vial) should be used.
1. Unscrew the syringe cap by twisting it anticlockwise.
2. Attach the needle to the syringe by gently connecting the needle hub into the LLA and rotate a quarter turn clockwise until the lock is felt.
3. Remove the needle protector, which may be stiff.
4. Add the solvent to the powder. The mixture should be well shaken until the powder is completely dissolved in the solvent.
After reconstitution, the vaccine should be used promptly.
5. Withdraw the entire contents of the vial.
6. A new needle should be used to administer the vaccine. Unscrew the needle from the syringe and attach the injection needle by repeating step 2.
Any unused product or waste material should be disposed of in accordance with local requirements.
After reconstitution, the vaccine should be injected immediately. If not used immediately, the reconstituted vaccine must be stored in a refrigerator between +2°C and +8°C and used within: 8 hours of reconstitution for the monodose presentation; 6 hours of reconstitution for the multidose (2 doses) presentation.
Incompatibilities: Priorix should not be mixed with other vaccines in the same syringe.