Zyrtec-D Use In Pregnancy & Lactation

Pregnancy: There are no adequate data on the use of cetirizine-pseudoephedrine in pregnant women. The use of pseudoephedrine during the first trimester of pregnancy has been associated with an increased frequency of gastroschisis (a developmental defect in the abdominal wall with intestinal herniation).
Due to the vasoconstrictive properties of pseudoephedrine, it should not be used during the third trimester as it can induce a reduction in uteroplacental circulation. Data on a limited number of exposed pregnancies indicate no adverse effects of cetirizine on pregnancy or on the health of the fetus/newborn child. There is insufficient animal data with respect to pregnancy, embryonal/fetal development, parturition or post natal development (see Pharmacology: Toxicology: Preclinic data under Actions). Zyrtec-D should not be used during pregnancy and is contraindicated in the third trimester of pregnancy.
Lactation: Cetirizine and pseudoephedrine are excreted into human milk. Therefore, Zyrtec-D should not be used during lactation.