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Administration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
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Contraindications
Hypersensitivity to cefprozil, or other cephalosporins.
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Special Precautions
Patient with history of penicillin allergy, gastrointestinal disease (particularly colitis). Renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor renal function at baseline and as clinically indicated. Monitor for signs and symptoms of anaphylaxis during 1st dose.
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Adverse Reactions
Significant: Hypersensitivity, fungal or bacterial superinfection, including pseudomembranous colitis, Clostridium difficile-associated diarrhoea (prolonged use).
Gastrointestinal disorders: Diarrhoea, nausea, vomiting, abdominal pain.
Investigations: Increased serum transaminases.
Nervous system disorders: Dizziness.
Skin and subcutaneous tissue disorders: Diaper rash, genital pruritus.
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Drug Interactions
May enhance the nephrotoxic effect of aminoglycosides. Increased serum concentrations with probenecid.
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CIMS Class
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ATC Classification
J01DC10 - cefprozil ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
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