Contraindications
Hypersensitivity. Myasthenia gravis.
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Special Precautions
Patients w/ renal impairment, porphyria. Pregnancy and lactation. Patient Counselling Due to neurologic disturbances that may occur, if affected, do not drive or operate machinery. Monitoring Parameters Monitor serum creatinine and BUN regularly while on treatment.
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Adverse Reactions
Superinfection; renal damage; visual disturbances; GI disturbances, dizziness, nausea, vomiting; confusion, peripheral neuropathy; respiratory insufficiency and muscle weakness.
Potentially Fatal: Severe colitis. |
Drug Interactions
Potentiates action of curariform muscle relaxants. Increased nephrotoxicity w/ aminoglycosides, amphotericin B, capreomycin, vancomycin.
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CIMS Class
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ATC Classification
A07AA10 - colistin ; Belongs to the class of antibiotics. Used in the treatment of intestinal infections.
J01XB01 - colistin ; Belongs to the class of polymyxins. Used in the systemic treatment of infections. |