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Administration
May be taken with or without food.
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Contraindications
History of depression, pre-existing symptoms of Parkinson's disease, other extrapyramidal disorders.
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Special Precautions
Not indicated for acute migraine attacks. Hepatic impairment. Elderly. Patient Counselling This drug may cause CNS depression, if affected, do not drive or operate machinery. Monitoring Parameters Monitor for signs and symptoms of depression, and extrapyramidal symptoms.
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Adverse Reactions
Significant: Depression, extrapyramidal symptoms; mild increase in serum prolactin levels and menstrual irregularities. Rarely, galactorrhoea.
Gastrointestinal disorders: Dry mouth, nausea, vomiting, stomach pain.
Investigations: Weight gain.
Metabolism and nutrition disorders: Increased appetite.
Musculoskeletal and connective tissue disorders: Myalgia.
Nervous system disorders: Drowsiness, dizziness.
Psychiatric disorders: Insomnia.
Skin and subcutaneous tissue disorders: Rash.
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Drug Interactions
Increased risk of excessive sedation with CNS depressants. May increase therapeutic effects of antihypertensive drugs. May increase the risk of galactorrhoea with oral contraceptives.
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CIMS Class
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ATC Classification
N07CA03 - flunarizine ; Belongs to the class of antivertigo preparations.
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