Contraindications
Hypersensitivity, malignancy. Direct application to the cornea, reduction of swelling of bites or stings. Inj into or around infected area. IV admin; unexplained premature labour.
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Special Precautions
Impaired renal function. Infants, elderly. Patients with infections. Pregnancy, lactation.
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Adverse Reactions
Urticaria, occasional severe allergy.
Potentially Fatal: Hypersensitivity and anaphylaxis. |
Drug Interactions
Action potentiated by urokinase especially in the treatment of MI. May increase absorption and toxicity of local anaesthetics. Heparin, salicylates and NSAIDs may inhibit the spreading action and efficacy of hyaluronidase.
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CIMS Class
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ATC Classification
B06AA03 - hyaluronidase ; Belongs to the class of enzymes used as hematological agent.
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