Lincomycin

Should be taken on an empty stomach. Take w/ full glass of water on an empty stomach 1 hr before or 2 hr after meals.

Hypersensitivity to lincomycin or clindamycin.

Patient w/ history of GI disease particularly colitis, history of asthma or significant allergies. Severe renal and/or hepatic impairment. Pregnancy and lactation. Monitoring Parameters Periodically perform LFTs, kidney function tests and blood cell counts during prolonged therapy.

Nausea, vomiting, diarrhoea, abdominal pain, tenesmus, glossitis, stomatitis, pruritus ani; rash, vaginitis, leucopenia, neutropenia, agranulocytosis, eosinophilia, thrombocytopaenic purpura; transient increases in serum bilirubin, alkaline phosphatase, and AST, jaundice, headache, myalgia, tinnitus, dizziness, vertigo, azotemia, oliguria, proteinuria, hypotension, syncope; reversible increases in serum creatine kinase (CK) and creatine phosphokinase (CPK); induration, and sterile abscess on inj site w/ IM admin. Rarely, erythema multiforme resembling Stevens-Johnson syndrome, exfoliative and vesiculobullous dermatitis, cardiopulmonary arrest, aplastic anaemia, pancytopenia; thrombophlebitis, erythema, pain and swelling w/ IV admin.
Potentially Fatal: Clostridium difficile-associated diarrhoea and colitis, serious anaphylactoid reactions.

May potentiate effects of neuromuscular blocking agents (e.g. pancuronium, tubocurarine). Reduced GI absorption w/ kaolin. May antagonise the effect of erythromycin.

Other Antibiotics

J01FF02 - lincomycin ; Belongs to the class of lincosamides. Used in the systemic treatment of infections.