Contraindications
Ocular viral (e.g epithelial herpes simplex keratitis), fungal, and mycobacterial infection.
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Special Precautions
Patient w/ glaucoma, history of ocular herpes simplex. Pregnancy and lactation. Patient Counselling Remove contact lenses prior to ophth admin and reinsert after 15 min. This drug may cause transient effects on vision, if affected, do not drive or operate machinery. Monitoring Parameters Monitor intraocular pressure (if used for >10 days); signs and symptoms of other infections (e.g. fungal).
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Adverse Reactions
Significant: Increased ocular pressure, optic nerve injury, visual acuity and field of vision defect, posterior subcapsular cataract formation, corneal or scleral thinning, delayed wound healing, secondary ocular infection (e.g. bacterial, viral, fungal infection).
Nervous: Headache.
Resp: Pharyngitis, rhinitis.
Ophthalmologic: Application site burning, foreign body sensation, chemosis, anterior chamber inflammation, blurred vision, epiphora, eye discharge, photophobia, visual disturbance, xerophthalmia, conjunctival hyperaemia, corneal oedema, eye pain, blepharitis, conjunctivitis, corneal changes, eye irritation, keratoconjunctivitis, uveitis, conjunctival papillae.
Dermatologic: Pruritus.
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Drug Interactions
May increase the risk of intraocular pressure w/ cycloplegics and other ocular hypotensive agents.
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CIMS Class
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