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Contraindications
Pulmonary congestion or oedema; intracranial bleeding; CHF; metabolic oedema with abnormal capillary fragility; anuria due to severe renal disease; severe dehydration.
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Special Precautions
Hypervolaemia; urinary tract obstruction; check for signs of fluid and electrolyte imbalance. Should not be administered with whole blood. Pregnancy, lactation.
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Adverse Reactions
Fluid and electrolyte imbalance; acidosis (with high doses). Nausea, vomiting, thirst; headache, dizziness, convulsions, chills, fever; tachycardia, chest pain; blurred vision; urticaria and hypotension or hypertension; acute renal failure; skin necrosis; thrombophloebitis.
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Drug Interactions
Increased nephrotoxicity with ciclosporin.
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CIMS Class
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ATC Classification
V04CX04 - mannitol
R05CB16 - mannitol ; Belongs to the class of mucolytics. Used in the treatment of wet cough. B05CX04 - mannitol ; Belongs to the class of other solutions used as irrigating solutions. B05BC01 - mannitol ; Belongs to the class of solutions producing osmotic diuresis used in I.V. solutions. A06AD16 - mannitol ; Belongs to the class of osmotically acting laxatives. |
