Mebendazole


Generic Medicine Info
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Pregnancy. Concomitant use with metronidazole.
Special Precautions
Patient with Crohn's ileitis or ulcerative colitis. Hepatic impairment. Children. Lactation. Monitoring Parameters Monitor CBC when used at higher doses and for a prolonged duration. Check for helminth ova in faeces within 3-4 weeks after the initial therapy.
Adverse Reactions
Significant: Reversible liver function disturbances, hepatitis, neutropenia, agranulocytosis. Gastrointestinal disorders: Abdominal pain, diarrhoea, flatulence, nausea, vomiting. Metabolism and nutrition disorders: Anorexia. Nervous system disorders: Dizziness, convulsions. Renal and urinary disorders: Glomerulonephritis. Skin and subcutaneous tissue disorders: Alopecia, angioedema, rash, urticaria.
Potentially Fatal: Rarely, toxic epidermal necrolysis, Stevens-Johnson syndrome.
Drug Interactions
Cimetidine may increase the plasma concentration of mebendazole.
CIMS Class
Anthelmintics
ATC Classification
P02CA01 - mebendazole ; Belongs to the class of benzimidazole derivative agents. Used as antinematodal.
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