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Administration
Should be taken with food.
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Contraindications
Symptomatic prostatic hypertrophy; neonates and premature infants.
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Special Precautions
May impair ability to drive or operate machinery. Has potential for abuse. Narrow angle glaucoma, asthma or severe CV disease. Antiemetic effect may mask signs of other conditions. Pregnancy and lactation. Elderly.
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Adverse Reactions
Oral: Sedation. Hypersensitivity reactions. Lassitude, dizziness, tinnitus, inability to concentrate, incoordination, irritability, insomnia and tremors. Nausea, vomiting, diarrhoea, colic, epigastric pain, anorexia, dryness of mouth and constipation. Urinary retention. Palpitations, headache. Blurred vision, increased intraocular pressure. Muscular weakness. Rarely, blood dyscrasias e.g. agranulocytosis, haemolytic anaemia. Ophthalmic: Temporarily enlarged pupils, eye redness (overuse).
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Drug Interactions
May mask ototoxicity produced by aminoglycoside antibiotics.
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ATC Classification
D04AA16 - pheniramine ; Belongs to the class of topical antihistamines used in the treatment of pruritus.
R06AB05 - pheniramine ; Belongs to the class of substituted alkylamines used as systemic antihistamines. |
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