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Contraindications
Undergo trans-sphenoidal hypophysectomy or surgery exposing dura mater, narrow angle glaucoma, atrophic rhinitis. Children <6 years.
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Special Precautions
Patient with CV disease, hypertension, diabetes mellitus, hyperthyroidism, prostatic hyperplasia or urinary obstruction. Elderly, children >6 years. Pregnancy and lactation. Patient Counselling Avoid excessive or prolonged use.
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Adverse Reactions
Significant: Local irritation, burning sensation in the nose and throat, rebound congestion. Hallucinations, restlessness, sleep disturbances in children. Rarely, transient visual impairment, tachycardia.
Cardiac disorders: Palpitations.
Gastrointestinal disorders: Nausea.
General disorders and administration site conditions: Mucosal dryness.
Nervous system disorders: Headache.
Respiratory, thoracic and mediastinal disorders: Dry nose, nasal discomfort.
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Drug Interactions
Enhanced adverse effects with other sympathomimetics. Risk of hypertensive crisis with MAOIs or TCAs.
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ATC Classification
R01AB06 - xylometazoline ; Belongs to the class of topical sympathomimetic combination preparations, excluding corticosteroids. Used as nasal decongestants.
R01AA07 - xylometazoline ; Belongs to the class of topical sympathomimetic agents used as nasal decongestants. S01GA03 - xylometazoline ; Belongs to the class of sympathomimetics used as ophthalmologic decongestants. |
