Avodart Dosage/Direction for Use

Avodart can be administered alone or in combination with the alpha-blocker tamsulosin (0.4 mg).
The recommended dose of Avodart is one capsule (0.5 mg) taken orally once a day.
The capsules should be swallowed whole and not chewed or opened, as contact with the capsule contents may result in irritation of the oropharyngeal mucosa. The capsules may be taken with or without food. Although an improvement may be observed at an early stage, it can take up to 6 months before a response to the treatment can be achieved. No dose adjustment is necessary in the elderly.
Renal Impairment: The effect of renal impairment on dutasteride pharmacokinetics has not been studied. However, no adjustment in dosage is anticipated for patients with renal impairment (see Pharmacokinetics under Actions).
Hepatic Impairment: The effect of hepatic impairment on dutasteride pharmacokinetics has not been studied so caution should be used in patients with mild to moderate hepatic impairment (see Pharmacokinetics under Actions and Precautions). In patients with hepatic impairment, the use of dutasteride is contraindicated.