Clovertil Special Precautions

Accurate obstetric and gynecological examination must be carried out before treatment with Clomiphene citrate.
The patient must be informed of the existence the possibility of multiple pregnancies.
Administration of Clomiphene citrate must be stopped if there is a visual impairment, for example blurred eyes, spots or flashes arise (in rare cases, scotomata can occur).
Infertile patients due to endocrine disorders must be treated first before Clomiphene administration and it is recommended to carry out semen analysis in infertile couples who are undergoing ovulation induction therapy.
Close evaluation including pelvic examination must be carried out before administration of Clomiphene.
To reduce the risk of ovarian enlargement during administration of this drug, the dose need to be reduced.
Ovarian hyperstimulation syndrome such as: abdominal pain, gastrointestinal disorders, ovarian enlargement, weight gain, dyspnea, oliguria may occur in patients who get Clomiphene citrate for ovulation induction therapy.
Long-term use may increase the risk of ovarian tumors.