Sign Out
Several inhalation anesthetics, such as cyclopropane or halothane, may stimulate the hypotensive effect of oxytocin and reduce its oxytocic. Concomitant use with oxytocin can cause heart rate disturbance.
When given during or after caudal block anesthesia: Oxytocin can amplify the effect of the pressure of sympathomimetic vasoconstrictor agents.
Prostaglandins and analogues: prostaglandins and analogs facilitate contraction in the myometrium, thereby increases the effects of oxytocin and prostaglandin analogs on the uterus.
Drugs that prolong the QT interval: Oxytocin is potentially arrhythmogenic, especially in patients with other risk factors for "torsade de pointes" such as drugs that prolong QT interval or patients with long QT syndrome (see Precautions).
