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Oxytocin should not be used for long periods in patients with severe cardiovascular disorders. Oxytocin should not be given as a bolus IV injection. This can lead to short-term acute hypotension accompanied by "flushing" and tachycardia.
Cardiovascular impairment: oxytocin should be used with caution in patients who have myocardial ischemia pre-disposition due to cardiovascular disease (such as hypertrophic cardiomyopathy, valvular heart disease and/or ischemic heart disease includes vasopasme coronary arteries), in order to avoid significant changes in blood pressure and heart rate in patients.
QT Syndrome: oxytocin given with caution in patients known to have "long QT syndrome" or related symptoms and patients taking drugs that prolong the QTc interval (see Interactions).
Effects on ability to drive: It should be cautious when it comes to driving or operating machinery.
