If the child is allergic to one of the vaccine's components, or to pertussis vaccines (acellular or whole cells pertussis), or if the child experienced an allergic reaction after injection of a vaccine containing the same substances.
Known hypersensitive to glutaraldehyde, neomycin, streptomycin, or polymyxin B (used during the manufacturing process and which may be present as traces).
If the child suffers from evolving encephalopathy (cerebral lesions).
If the child suffered from encephalopathy (cerebral lesions) within 7 days of a previous dose of a pertussis vaccine (acellular or whole cells pertussis).
If the child has a fever or an acute disease (the vaccination must be postponed).