Volteri Dosage/Direction for Use

For adults, orally administer one tablet once daily (8 mg/5 mg as candesartan cilexetil/amlodipine). Do not use this drug as a primary drug for the treatment of hypertension.
Precautions for Dosage & Administration: Dosage should be determined for each patient based on the following dosage and administration of candesartan cilexetil and amlodipine besilate.
Candesartan cilexetil: Hypertension: Usually, for adults, a dose of 4 - 8 mg of candesartan cilexetil is orally administered once a day. The dosage may be increased up to 12 mg if necessary. For patients with renal dysfunction, the starting dose is 2 mg once a day and may be increased up to 8 mg if necessary.
Amlodipine besilate: Hypertension: Usually, for adults, a dose of 2.5 - 5 mg of amlodipine is orally administered once a day. The dosage may be appropriately adjusted according to the patient's symptom, and dose can be increased up to 10 mg once a day when the effect is insufficient.
In principle, switching to Volteri Tablets should be considered when candesartan cilexetil 8 mg and amlodipine 2.5-5 mg are coadministrated, or when the blood pressure is not controlled sufficiently by administration of one of them.