Alduet

Alduet

Manufacturer:

Ajanta Pharma Phil

Distributor:

Ajanta Pharma Phil
Concise Prescribing Info
Contents
Montelukast Na 10 mg, cetirizine HCl 10 mg
Indications/Uses
Symptomatic relief associated w/ seasonal & perennial allergic rhinitis & chronic urticaria.
Dosage/Direction for Use
Adult & childn >12 yr 1 tab once daily. Patient w/ hepatic & renal impairment Reduce to ;½ of usual daily dose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to montelukast, cetirizine HCl, hydroxyzine or any piperazine derivatives. Severe renal impairment (CrCl <10 mL/min).
Special Precautions
Pregnancy & lactation. Montelukast: Do not use to treat acute asthma attacks. Do not substitute abruptly for inhaled or oral corticosteroids. May cause systemic eosinophilia, sometimes presenting w/ clinical features of vasculitis consistent w/ Churg-Strauss syndrome; treatment should be reassessed and evaluated if patient develops these symptoms. Cetirizine: Patients w/ predisposition factors or urinary retention (eg, spinal cord lesion, prostatic hyperplasia); epileptic patients & patients who are at risk of convulsions. Concomitant use w/ alcohol. A wash out period of 3 days is required before performing allergy skin test. May affect the ability to drive & use machine.
Adverse Reactions
Montelukast: Upper resp infection. Diarrhoea, nausea, vomiting; rash; elevated ALT & AST levels; pyrexia. Cetirizine: Somnolence, fatigue, dizziness & headache.
Drug Interactions
Montelukast: Co-administration w/ CYP3A4, 2C8 & 2C9 inducers eg, phenytoin, phenobarb, rifampicin (particularly in childn). Increased systemic exposure w/ gemfibrozil. Decreased rate of absorption w/ food.
MIMS Class
Antihistamines & Antiallergics
ATC Classification
R03DC53 - montelukast, combinations ; Belongs to the class of leukotriene receptor antagonists. Used in the systemic treatment of obstructive airway diseases.
Presentation/Packing
Form
Alduet FC tab
Packing/Price
30's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in