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Patients with Renal Impairment: There is no need to adjust the dose of amlodipine in patients with renal disease since once-daily administration of Amlokard is found to be suitable for all degrees of renal functions.
Patients with Hepatic Impairment: In the presence of hepatic impairment, dosage of amlodipine should be adjusted to 2.5 mg/day.
Use in lactation: There is no available data yet confirming the excretion of amlodipine in breast milk. Caution should be taken when giving Amlokard to lactating mothers.
Use in children: In a study done among hypertensive children with mean age of 12 years, amlodipine was found to effectively lower systolic blood pressure. The safety and efficacy of amlodipine in children <6 years has not yet been established.
Use in the elderly: Amlodipine is well tolerated in elderly hypertensive patients at a dose of 2.5 mg/day.
