Pregnancy: No clinical data on exposed pregnancies are available with exemestane. Studies in animals have shown reproductive toxicity (see Pharmacology: Toxicology: Preclinical safety data under Actions). Exemestane is therefore contraindicated in pregnant women.
Lactation: It is unknown whether exemestane is excreted in human milk. Exemestane should not be administered to lactating women.
Women of perimenopausal status or child-bearing potential: The physician needs to discuss the necessity of adequate contraception with women of childbearing potential, including women who are perimenopausal or have recently become postmenopausal, until their postmenopausal status is fully established (see Contraindications and Precautions).