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Tolerance may occur with prolonged use of Salbutamol, but temporary cessation of the drug restores its original effectiveness.
Combined therapy: Concomitant use of salbutamol with other sympathomimetic agents is not recommended, as it may lead to deleterious cardiovascular effects. This does not preclude the judicious use of an adrenergic stimulant aerosol bronchodilation or the relief of an acute bronchospasm in patients receiving salbutamol. Do not give on a routine basis. If regular administration is required, consider alternative therapy.
