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For bronchitis and pneumonia, the dosage is 250 mg administered three times daily. A dosage of 250 mg administered three times daily for 10 days is recommended for sinusitis. For more severe infections (such as pneumonia) or those caused by less susceptible organisms, doses may be doubled. Doses of 4 g per day have been administered safely to normal subjects for 28 days, but the total daily dosage should not exceed this amount. For the treatment of acute gonococcal urethritis in males and females, a single dose of 3 g combined with 1 g probenecid is given. Or as prescribed by the physician.
For children over 1 month, the usual recommended daily dosage is 20 mg/kg per day in divided doses every 8 hours. For bronchitis and pneumonia, the dosage is 20 mg/kg per day in divided doses administered three times daily. In more serious infections, otitis media and infections caused by less susceptible organisms, 40 mg/kg per day in divided doses are recommended, with a maximum dosage of 1 g per day or as prescribed by the physician.