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Stability in IV Fluids: Amikacin is stable for 24 hours at room temperature at concentrations of 0.25 and 5.0 mg/ml in the following solutions; 5% Dextrose Injection, 5% Dextrose Solution and 0.2% Sodium Chloride Injection, 5% Dextrose Solution and 0.45% Sodium Chloride Injection, 0.9% Sodium Chloride Injection, Lactated Ringer's Injection, Normosol R in 5% Dextrose Injection.
In the above solutions with amikacin concentrations of 0.25 and 5.0 mg/ml, solutions aged for 60 days at 4°C and then stored at 25°C had utility time of 24 hours.
At the same concentrations, solutions frozen and aged for 30 days at -15°C and stored at 25°C had utility time of 24 hours.
