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Pregnancy: There is a limited amount of data from the use of clotrimazole in pregnant women. Animal studies with clotrimazole have shown reproductive toxicity at high oral doses. At the low systemic exposures of clotrimazole following topical treatment, harmful effects with respect to reproductive toxicity are not predicted. Clotrimazole can be used during pregnancy but only under the supervision of a physician or midwife.
Lactation: Available pharmacodynamic/toxicological data in animals have shown excretion of clotrimazole / metabolites in milk after intravenous administration. A risk to the sucking child cannot be excluded. A decision must be made whether to discontinue breast feeding or to discontinue/abstain from clotrimazole therapy taking into account the benefit of breast-feeding for the child and the benefit of therapy for the women.
