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Dalamax

Dalamax

clindamycin

Manufacturer:

Interphil

Distributor:

MedChoice Women's Health
Concise Prescribing Info
Contents
Clindamycin HCl
Indications/Uses
Treatment of serious anaerobic infections due to Bacteroides fragilis, staphylococcal & streptococcal infections.
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Dosage/Direction for Use
Adult 150-300 mg 6 hrly. Severe infections 300-450 mg 6 hrly. Childn 3-6 mg/kg body wt 6 hrly, <12 mth or weighing ≤10 kg 37.5 mg 8 hrly.
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Administration
May be taken with or without food: Swallow whole w/ a full glass of water & in an upright position.
Contraindications
Hypersensitivity to clindamycin or lincomycin. Patients w/ GI disease especially w/ history of colitis; diarrhea.
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Special Precautions
Discontinue use if diarrhea & colitis develops. Renal & hepatic impairment. Monitor blood counts, renal & liver function on prolonged treatment. Pregnancy & lactation. Childn. Elderly.
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Adverse Reactions
Abdominal pain or cramps, nausea, vomiting, diarrhea & loose stools. Antibiotic-associated pseudomembranous colitis. Skin rashes & urticaria, SJS, anaphylaxis, transient leucopenia, leucopenia w/ agranulocytosis, eosinophilia, thrombocytopenia, erythema multiforme, exfoliative & vesiculobullous dermatitis, polyarthritis, abnormal LFT, overt jaundice, hepatic damage.
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Drug Interactions
Increased risk of resp depression w/ tubocurarine, pancuronium & atracurium. Delayed excretion of toxin w/ diphenoxylate, loperamide & other opiate antidiarrheal drugs. Reduced absorption w/ kaolin-pectin susp. Inhibited in vitro activity of aminoglycosides. Antagonized activity of parasympathomimetics eg, neostigmine & pyridostigmine.
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Storage
View Dalamax storage conditions for details to ensure optimal shelf-life.
Description
View Dalamax description for details of the chemical structure and excipients (inactive components).
Action
View Dalamax mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Other Antibiotics
ATC Classification
J01FF01 - clindamycin ; Belongs to the class of lincosamides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Dalamax cap 300 mg
Packing/Price
100's (P42.5/cap, P4,250/box)
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