No overall effect on rat fertility was observed with Desloratadine at an exposure that was 34 times higher than the exposure in humans at the recommended clinical dose. No teratogenic or mutagenic effects were observed in animal trials with Desloratadine. Since no clinical data on exposed pregnancies are available with Desloratadine, the safe use of Desloratadine tablets during pregnancy has not been established. Desloratadine is excreted into breast milk, therefore the use of Desloratadine tablets are not recommended in breast-feeding women.
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